![]() Recently, a widely viewed social media post jumped to the conclusion that the study shows that “a higher number of COVID-19 vaccine doses received increases the risk of infection with COVID-19.” Another widely viewed post sharing the study results incorrectly concluded that the vaccines were a “ failed experiment.” Incorrect claims about the paper have been circulating since before it was peer-reviewed and published. And studies have generally found that each additional vaccine dose reduces COVID-19 risk. Rather, this finding was an association that could be due to multiple other factors. But the researchers didn’t find that more doses caused a higher risk of infection. ![]() 12, 2022 - the day the bivalent booster became available at the Cleveland Clinic - had a higher rate of testing positive in the following months than people who had gotten fewer prior vaccine doses. ![]() The researchers also noticed that people who got more vaccine doses prior to Sept. The bivalent booster prompts the immune system to recognize both the original spike protein of the virus and the version found on BA.4 and BA.5, the predominant omicron subvariants when it was first rolled out. It concluded the booster provided some protection. They also offer some protection against infections, although the effectiveness wanes in the months after getting vaccinated, and such effectiveness is lower against the omicron variant, compared with earlier variants of the coronavirus.Īn observational study of more than 50,000 Cleveland Clinic staff published recently in Open Forum Infectious Diseases aimed to assess the effectiveness of the bivalent omicron booster against infection between September 2022 and March 2023, a period when 8.7% of the employees tested positive. Those who had received a booster vaccine dose as well had a 94% lower risk.ĬOVID-19 vaccines and boosters reduce the risk of severe disease and death. For instance, a Centers for Disease Control and Prevention study found that during the omicron wave, adults who had received two doses of the Pfizer/BioNTech or Moderna vaccines had a 79% lower risk of dying or needing a ventilator if hospitalized with COVID-19, compared with unvaccinated adults. The shots are still good at preventing hospitalization or death, though, particularly if someone has received a booster dose.īooster shots are recommended for most people, as these increase and prolong protection against severe disease and also provide some temporary protection against infection and milder illness. Against omicron, however, the vaccines haven’t fared as well and are much worse at preventing infection or mild disease. Subsequent studies have demonstrated that the vaccines are effective under real-world conditions, including against the highly contagious delta variant. The Novavax vaccine, which was authorized in July 2022, had a 90.4% efficacy in preventing symptomatic COVID-19 in adults, prior to the emergence of the omicron variant. Johnson & Johnson, which partly tested its vaccine in South Africa when the beta variant emerged, reported an efficacy of 66% in preventing moderate to severe COVID-19 and an efficacy of 85% in preventing severe or critical COVID-19 in its clinical trial. ![]() The Moderna vaccine showed similar results in its clinical trial, with a final efficacy of 93%. For example, the Pfizer/BioNTech vaccine, which was the first COVID-19 vaccine to receive full approval from the Food and Drug Administration, showed a final efficacy of 91% against symptomatic illness in its phase 3 trial, meaning that under the conditions of the trial the vaccine reduced the risk of getting sick by 91%. Īgainst earlier forms of the coronavirus, the vaccines were highly effective at preventing symptomatic illness. All of the authorized and approved vaccines are effective at preventing severe COVID-19. ![]()
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